THE CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES Chronic Aseptic Meningitis in a Patient with Systemic Lupus Erythematosus
نویسندگان
چکیده
Chronic aseptic meningitis is a rare manifestation of systemic lupus erythematosus. It may occur early in the course of the disease and sometimes may be the initial symptom. We report a patient with chronic aseptic meningitis associated with systemic lupus erythematosus. Magnetic resonance imaging showed several ischemic lesions and an appearance which was compatible with chronic inflammation of the ependyma of the lateral ventricles. RESUME: Meningite aseptique chronique chez un patient atteint de lupus erythemateux aigu dissemine La meningite chronique aseptique est une manifestation rare du lupus erythemateux aigu dissemine. Elle peut survenir tot dans revolution de la maladie et peut parfois en etre le premier symptome. Nous rapportons les cas d'un patient atteint de meningite chronique aseptique associee a un lupus erythemateux aigu dissemine. L'imagerie par resonance magnetique a montre plusieurs lesions ischemiques et un aspect compatible avec une inflammation chronique de l'ependyme des ventricules lateraux. Can. J. Neurol. Sci. 1989; 16: 354-356 Central nervous system (CNS) involvement in patients with systemic lupus erythematosus (SLE) is common, occurring in between 20-75% of cases.Although any part of the central and peripheral nervous system may be involved, one of the least common manifestations is chronic aseptic meningitis. It may occur early in the course of the disease, and at times can be the initial symptom, in contrast to bacterial meningitis which appears as a late complication in association with corticosteroid therapy. We report here a patient with chronic aseptic meningitis as a manifestation of SLE, and discuss the magnetic resonance imaging (MRI) findings which were compatible with that diagnosis. We are not aware of any previous publications describing the MRI findings in chronic aseptic meningitis associated with SLE.
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